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16631 – This invention is an RNA-based genetic circuit which can produce antigens or numerous proteins including: therapeutic, cell death, fluorescent, and selection proteins. This technology may be used for a number of applications including, but not limited to, selective stem cell reprogramming or vaccination.
17809 – Programming mammalian cells with large synthetic gene networks can significantly facilitate elucidating complex regulatory cellular mechanisms, implementing new useful biological functions and accelerating the design of novel tailor-made therapeutic treatments. Complex, stable and heritable programming of mammalian cells by genomic engineering is limited by the requirement to... Read More
16593 – This invention produces oligonucleotides for the self-assembly of DNA nanostructures for a variety of uses. Functional DNA nanostructures have a number of applications, including, but not limited to, scaffolds for the organization of materials, synthesis of organic elements, control of biomineralization, drug delivery, and intracellular sensors. In vivo implementation has been... Read More
14321 – This invention may be applied to the targeted destruction of cancer cells. Current cancer treatments utilize a non-specific approach which inflicts damage on heathy tissue during the process of killing cancer cells. In addition, this general approach often requires multiple treatments causing further damage to healthy cells. This invention uses a RNAi-enhanced genetic logic... Read More