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The MIT Technology Licenses Office welcomes companies to get to know us personally. We find it most effective to work individually with a company to identify specific areas of interest. We then bring inventions, which specifically match the company's interests to the attention of the company. With 500 new invention disclosures coming into our office each year, our portfolio is constantly changing. The technologies highlighted here do not encompass our entire portfolio. We therefore encourage companies to keep in touch on a regular basis and also to contact us when a particular technology need arises.
Our technology is usually early stage and often requires substantial development by the licensing company before a commercial product is ready for market. Because of this, we often find that the best contact person from the company is one who is knowledgeable about the company's science and technology and also familiar with the long-term strategic plans of the company.
16279 – Research aimed at understanding the brain and nervous system’s activity depends on neural recording devices such as neural probes and implants. Current implanted neurological technologies are highly invasive in their nature and often prompt an immediate inflammatory response, indicating a need for more compact, yet functional, platforms that are capable of accessing specific... Read More
17020 – Two rhenium complexes have shown high potency and efficacy in the treatment of chemotherapeutic-resistant cancers Chemotherapies are one of a few available and established treatment options for those fighting cancer. Platinum-based chemotherapies, such as cisplatin, are some of the oldest cancer therapeutic options; they work by cross-linking nuclear DNA and inducing... Read More
16856 – Human capability to learn new information is often slow, laborious, and error-prone, particularly in cases involving memory disorders such as Alzheimer’s disease or age-related memory loss. Existing processes of memory enhancement and disruption are limited to shock therapy, which is dangerous and well-known for its severe side-effects. Currently, there are no means for... Read More
17339 – In vivo animal studies are an essential part of the preclinical phase of the drug discovery process. Currently, there are no means for high-throughput characterization of biologics using in vivo animal models. The technology presented here provides a large-scale in vivo assessment platform that controls delivery of a drug to desired organs of a group of animals to enable... Read More
11841-12720 – A great variety of neurodevelopment diseases are caused by genetic mutation in the MECP2 gene. As an example, Rett Syndrome is a rare genetic neurological disorder that predominantly affects 1 out of 10,000 to 15,000 newborn girls. Mutations in the MECP2 gene in Rett patients delay neural and synaptic maturation leading to extended brain plasticity. This condition is characterized by... Read More
17410 – Flexible endoscopic surgery requiring an obstruction-free surgical field and precise control of flexible surgical instrumentation including laser fibers, graspers, scissors, and soft tissue dissectors introduced via the working channel of the endoscope. Though flexible endoscopes with working channels have allowed minimally invasive surgeries to be performed, the complexity of the... Read More
16966 – The methodology can be applied in surgeries, where temporary suspension of blood coagulation is necessary, such as transplants, or on demand for externally controlled rapid halting of bleeding. Treatment of bleeding disorders and surgery blood clotting must be controlled for patient safety. This invention allows reversible control of blood coagulation, using nanoparticles and laser... Read More
13523 – This invention is useful for microwave, integrated optical and photonic circuits, and other optical applications. Photonic crystals are structures with periodicity comparable to the wavelength of light. They possess many technologically important optical properties and can suppress back scattering in optical waveguides. The invention is a waveguide that includes a photonic... Read More
16540 – Applications for this technology are found in photonic I/O for computing devices, such as CPUs and DRAM on CMOS processes. For photonic I/O to make a major commercial impact, they need to be compatible with standard advanced CMOS. While the compatibility with CMOS has been demonstrated for passive photonic, realizing active photonics, including modulators and detectors on CMOS, is the... Read More
16554 – Applications for this technology are found in chemical engineering, industrial water treatment, and power. The global demand for a steady economical supply of fresh water continues to increase. One of the main known modes of increasing the existing water supply is seawater desalination: a proven process that can reliably convert the seemingly limitless supply of seawater to high... Read More