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The MIT Technology Licenses Office welcomes companies to get to know us personally. We find it most effective to work individually with a company to identify specific areas of interest. We then bring inventions, which specifically match the company's interests to the attention of the company. With 500 new invention disclosures coming into our office each year, our portfolio is constantly changing. The technologies highlighted here do not encompass our entire portfolio. We therefore encourage companies to keep in touch on a regular basis and also to contact us when a particular technology need arises.
Our technology is usually early stage and often requires substantial development by the licensing company before a commercial product is ready for market. Because of this, we often find that the best contact person from the company is one who is knowledgeable about the company's science and technology and also familiar with the long-term strategic plans of the company.
18737 – The inventors have developed an injectable and degradable hydrogel that would release drugs selectively and locally to cancer cells in a sustained manner. Chemotherapy is an effective cancer treatment modality. However, side effects due to non-cancerous cell toxicity are extremely devastating for patients. Biomaterials have been increasingly used as vehicles for intravenous delivery of... Read More
18253 – This invention presents ingestible origami robots that can be controlled to move, manipulate, and accomplish clinically relevant tasks, such as removing a foreign body and patching a wound in the stomach. There has been considerable progress in interventional technologies for the gastrointestinal tract; large efforts are being directed towards microsurgical tools that are minimally... Read More
15785 – This technology describes a novel class of 3D molecular-layered nanoporous materials (High Definition Nanomaterials, or HDnanomaterials) that can be used to construct fluidic devices capable of isolating and manipulating nanometer-scale particles suspended in a fluid. Such devices have applications in areas including clinical diagnostics and treatment monitoring (e.g., manipulation of HIV... Read More
17896 – This technology automatically diagnoses skin cancer through tissue characterization. This invention has applications for dermatologists, non-specialists like physicians and nurse practitioners, and patients who are able to perform self-measurement. Melanoma is a dangerous disease that affects millions of people every year. It is clear that the single most promising strategy to reduce... Read More
18042 – The inventors have developed a microfluidic device which allows for the formation of neuromuscular junctions in a microenvironment. This device helps unravel the mechanisms leading to various neurodegenerative disorders by closely recapitulating the physiology of the neuromuscular tissue. Neuromuscular junctions (NMJs) are the fundamental physiologic structures responsible for... Read More
17704 – This invention is a system for monitoring sedation state and detecting adverse events during procedural sedation. The system can be implemented in a standalone monitor or incorporated into commercially available monitoring systems within clinical settings. Procedural sedation has allowed many painful procedures to be conducted outside the operating room. During such procedures, it is... Read More
9044 – Granulocyte colony-stimulating factor (G-CSF) analogs can be used in vivo to regulate the hematopoietic and immune systems, and to treat any condition characterized by a reduced hematopoietic or immune function, including a variety of hematopoietic, neurological, and reproduction related conditions. They can also be used in vitro to culture and mobilize hematopoietic cells, such as bone... Read More
17894 – This invention describes a 3D printing system that forms an object by filling a customized matrix with a curing casting material or a liquid filler material with desirable properties. 3D printing is a rapidly growing fabrication method to readily create structures across a range of applications. The process has the advantage of quickly generating parts that can be designed and... Read More
16528 – The inventors have developed a method to obtain nanosized crystalline or amorphous active pharmaceutical ingredients (APIs) in a controlled solid state form in porous excipient materials. This technology is suitable to develop drug products with enhanced solubility and dissolution rates for improved bioavailability. This invention has the potential to bring new drug discoveries to... Read More
16879 – The inventors have developed a device that tracks the location and detailed trajectory of radio frequency sources (e.g. RFIDs) moving in 3D space. This device can transform any plane or surface into a virtual touch screen, whereby users can interact with a desired computing device by gesturing or writing commands in the air. This interface can be used to interact with a remote screen, to... Read More