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The MIT Technology Licenses Office welcomes companies to get to know us personally. We find it most effective to work individually with a company to identify specific areas of interest. We then bring inventions, which specifically match the company's interests to the attention of the company. With 500 new invention disclosures coming into our office each year, our portfolio is constantly changing. The technologies highlighted here do not encompass our entire portfolio. We therefore encourage companies to keep in touch on a regular basis and also to contact us when a particular technology need arises.
Our technology is usually early stage and often requires substantial development by the licensing company before a commercial product is ready for market. Because of this, we often find that the best contact person from the company is one who is knowledgeable about the company's science and technology and also familiar with the long-term strategic plans of the company.
18042 – The inventors have developed a microfluidic device which allows for the formation of neuromuscular junctions in a microenvironment. This device helps unravel the mechanisms leading to various neurodegenerative disorders by closely recapitulating the physiology of the neuromuscular tissue. Neuromuscular junctions (NMJs) are the fundamental physiologic structures responsible for... Read More
17704 – This invention is a system for monitoring sedation state and detecting adverse events during procedural sedation. The system can be implemented in a standalone monitor or incorporated into commercially available monitoring systems within clinical settings. Procedural sedation has allowed many painful procedures to be conducted outside the operating room. During such procedures, it is... Read More
17894 – This invention describes a 3D printing system that forms an object by filling a customized matrix with a curing casting material or a liquid filler material with desirable properties. 3D printing is a rapidly growing fabrication method to readily create structures across a range of applications. The process has the advantage of quickly generating parts that can be designed and... Read More
16528 – The inventors have developed a method to obtain nanosized crystalline or amorphous active pharmaceutical ingredients (APIs) in a controlled solid state form in porous excipient materials. This technology is suitable to develop drug products with enhanced solubility and dissolution rates for improved bioavailability. This invention has the potential to bring new drug discoveries to... Read More
16879 – The inventors have developed a device that tracks the location and detailed trajectory of radio frequency sources (e.g. RFIDs) moving in 3D space. This device can transform any plane or surface into a virtual touch screen, whereby users can interact with a desired computing device by gesturing or writing commands in the air. This interface can be used to interact with a remote screen, to... Read More
17184 – Extracellular matrix (ECM) gels that can be formed and dissolved on demand by using methods accessible to the general cell biology community could be used in vitro to model complex human physiology in cell culture for biomedical research. Fast dissociation of the ECM is especially important when measuring and interpreting fast-changing cell signaling networks. Scientists have... Read More
17992 – This invention presents a method of ablating a target tissue using an electrical pulse regime that induces cell permeabilization and cell death, as a result of electroporation. Irreversible electroporation is a non-thermal injury ablative modality that is used in the treatment of locally advanced soft tissue tumors. This technique has been successfully performed intraoperatively,... Read More
17459 – This invention presents methods and systems for designing and building miniaturized Raman spectroscopic systems for detection of various bioanalytes, including blood glucose from the middle ear vasculature. Raman spectroscopy has been successfully employed to detect molecular species embedded in complex biological samples due to its inherent selectivity, multiplexed capabilities and... Read More
16488 – The inventors have developed a method to turn effectively any object into a visual microphone to enable the detection of sound from afar. Sound signals produce air pressure fluctuations that cause objects in the vicinity to vibrate. This method works by analyzing video recordings of these vibrations to convert them back into a corresponding sound signal. This technology is mainly... Read More
18702 – Memory retrieval by targeted brain stimulation may provide a means to treat the early stages of Alzheimer's disease (AD) and other neurological diseases where patients show memory loss. Currently, episodic memory deficits in pathological conditions, for example AD, are treated by medications, such as cholinesterase inhibitors or memantine, that lessen or stabilize cognitive function for... Read More